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Summary: Histone lysine demethylases (KDMs) play critical roles in oncogenesis and therefore may be effective targets for anticancer therapy. Using a time-resolved fluorescence resonance energy transfer demethylation screen assay. in combination with multiple orthogonal validation approaches. we identified geldanamycin and its analog 17-DMAG as KDM inhibitors. https://www.diegojavierfares.com/mega-choice-Seattle-Seahawks-NFL-Printed-Camo-Socks-p11205-top-buy/

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