Keep an eye on Carefully (1)pentobarbital will reduce the level or effect of benzhydrocodone/acetaminophen by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Warning when discontinuing CYP3A4 inducers that happen to be coadministered with benzhydrocodone (prodrug of hydrocodone); plasma concentrations of hydrocodone may well raise and may result... https://paula963lno3.newsbloger.com/profile